Obviously this means he's not some big demon you can fight in the game, but when you get to Subway Town and go to the back with I think... The old lady named Seri? She's smoking from some sort of pipe, and the canister type thing at the bottom is the picture of the Cyber-Demon from the cover of DOOM II.
Personally I like how the game is filled with small things like this, the Pinkies and the Quaola Crayons. Little things that give you a smile when you see them but don't affect or take away the experience you get from the story and the game.