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Turn off mods.

Did the OP originally entail anything in his post? Other than the ellipse that is present, which doesn't help any of us...

Negative. But mod conflicts seem to be the issue. As someone who frequently deals with mod incompatibilities in games like Minecraft this instantly came to mind, but I can see how people who aren't used to frequent updates might not pick up on this right away.

SOME mods may still work, but certainly not all. Let the creators update them first.

Have to go on a mod hunt after work, played a little before bed last night and a constant CTD when entering the castle at the start.
Unless anyone else has this problem and can save me some grief and tell me it is a known bug.

I hope to hell it isnt the Bathing Beauties home as it will probably take a week in real time to move all my stored loot elsewhere.

And OP, try and actually be a bit more usefull with some form of info next time.