Every so often you can go back to Mehrune Dagon's Shrine. There will usually be 2 Daedric warriors that attack you outside the Shrine and 2 more Daedric chumps inside. You can get 4 hearts off of their dead bodies but I am not sure the time frame that the enemies will respawn again. Also there is some decent stuff to loot inside the shrine.
Decent stuff might be an understatement. I think they respawn every 15 days you don't go there. I try to wander up there at least once every game month... not for the hearts but the gear that spawns

. Gold & Ebony ingots, a very high level staff, and enchanted gear lying around everywhere. There are multiple chests including a very good boss chest. That place probably has the highest reward vs risk & highest reward vs time of any dungeon in the game

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