What it says in the title. VATS no longer works at all for me, on any weapon.

have you tried loading an earlier save to see if it does it?

have you tried creating a new character completely and seeing if it still does it?

The VATS issue is a common glitch from before the patch. I have yet to play it post-patch, so I can't say if it's actually disabled now, but try shooting your gun a few times, leaving and entering sneak mode, and generally trying to 'reset' VATs.

mines works and never has been disabled