I've had the Karthspire-CTD after 165! hours, where it always crashes near Karthspire after getting the task with Sky Haven Temple.
I've had the Abandoned Prison-CTD after 55 hours, where it always crashes at the bridge between the Abandoned Prison and Hillgrund's Tomb.
And now I've got the Riften-CTD after 75 hours where it always crashes in the Riften docks...
These are NO mod issues btw, all these CTDs only happen with the specific chars. I never had such issues with any other game before. So now I am finally giving up on Skyrim. Maybe I will come around again, when everything is patched up, but until then I can't deal with this [censored] anymore.
So, do I only attract bad luck regarding Skyrim or is anyone else as unfortunate as I am?