I play on adept settings.
How often have you been stuck somewhere because you couldn't figure something out? not many is the answer for me.
There are lots of things to do but it's all seems to easy. Combat is fine,although this maybe different for every body depending on how they play.
I'm talking more about other things where you have to use your brain to figure things out. There really isn't enough moments that require you to think too much.
Also another issue for me is that there are not enough alternate out comes for your actions, making a second playthrough a little predictable.
Don't get me wrong,iv'e more than got my moneys worth out of this game ,it's great. But after playing it for hours (295 hours with 2 characters,one at 66 and one at 25) these are the things i think would of made it better.
Playing through it again even using a different race and different perks just isn't "Different" enough

It also feels that the main quest is far too short when compared to the rest of the game. I tried leaving the main quest for as long as i could to level up my charcter first but it still felt like it was over far too soon.
What else could they do to make it more exciting for a second playthrough? With an epic single player game like this with lots of different races to try out it seems essential.