So with a few mods I've been experimenting with I ended up running itno a fort with 5 STACKED followers, outfitted with the best gear, all of which are at lvl 79 and deal 1000-4000 damage per hit, so we walk into a camp and I think "I'm broken, I couldn't possibly lose" So my 3 followers charge in with shields (they have around 450 health each), start slaughtering like expected while Serana and one of my other followers sit in the back with bows/spells and start pegging off the enemies. Then I start noticing "uh oh, the AI has been beefed so they're dodging arrows like mad" so we continue to fight, a follower outright dies half way through and then I hear a bunch of roaring in the distance and look up to see 5 dragons circling overhead.
Right after the computer runs out of memory and crashes

Just felt like sharing my story.