Quite a lot of, if not all, recent nvidia card users can't play the game in full screen mode.
When full screen is ticked on launcher menu or specified as 1 in fallout4pref.ini, monitor screen flickers while the game trying to find a appropritate full screen resolution for the monitor and goes completely black after a few flickering. I can still hear the sound but screen is black.
This has been an issue with recent pc titles such as dragon age inquisition, battlefront, and now fallout 4 joined the club that doesn't support full screen mode for recent nvidia cards.
Many affected users asked around in geforce forum, intel graohic card forum, Microsoft forum, and EA forum for a fix but they only acknowledged the problem exists but haven't givne any fixes.
Dragon age inquisition doesn't support full screen mode for users who has a system with windows 8/8.1 + intel graphic card + nvidia optimus.
I think it's ridiculous to ignore and neglect pc users this way since pc buyers increased in number, taking up a good portion of user base.
I think it's a widely accepted fact that a fullscreen is better for overall performance than windowed mode.
Since FO4 is still very demanding due to its lack of optimization, I'd like to request for a full screen support for pc users.