I get the same problem. Until 1.2 came out I experienced no glitches. Now (after the patch) about every 30 seconds or so the game freezes on me (audio still plays fine). When I press the xbox button on my controller it seems to pull it out of the frozen state for some reason. Also, the very first companion quest where I train with that guy seemed to be what triggered the freezing for me. In addition, everyone I walk by thinks I pressed the talk button...kind of frustrating as well but it allows me to attack them with no penalty (easy training!

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Anyways I have faith in the dev team that this problem will be resolved, it's no different than the first 1st gen of anything - there's always bugs (look at Apple's SIRI for example). My fix is remove the patch, keep your previous games saved and just start a new game with a different character build.