I don't know what you mean. If you mean that you have tried to bind non-default keys to Skyrim (like changing Use from E to F), but the game's menus still show the default binds in prompts and menus (Press E to Sell, etc), then that is apparently intended behaviour.
This is the way of it, I'm afraid. We weighed the clarity of swapping out the button help with whatever the user had mapped versus the enormous amount of video memory required to load up every possible piece of button art every time you entered the Inventory, and speed/memory won out.
And no, that decision still does not make any sense at all, seeing as they could have decided to use text instead of pictures to represent all possible keys without any performance hit (possibly less of a hit than using any pictures in the first place). But hey, that's what happens when you've got a console port.
I am using a G13 with the G-keys bound to the default keys.