Well those who chose to be a vampire and completed the main quests of the Dawnguard DLC, later when you do all these side quests you get one that says to go to Markarth and change Cairine into a vampire... Well those who already did that and got the quest again simply go to here and kill her

lol
That's what I did and for some reason I got some inheritance like the game thought she was my wife but she wasn't, anyways after you kill her go back to Castle Volkihar and speak to Feran Sadri for the next quest