This has always been a concern of mine, tho in other games I could readily move things to compensate. My concern is that, I have to look down for my mana/health, center of my screen for my character, and the left of my screen for my teams health. This results in my eyes darting from one thing to the next in combat, I prefer everything to be centered on my screen as is my character.
Please make party frames MOVEABLE at launch!