usually the glitches are so weird though that I have no idea how anybody figures them out in the first place.
One of the Oblivion dupe glitches can be found by taking an item from one of a few specific chests, putting it back after finding out that it's not so great, and then picking it up again in order to sell it.
Another could be found by trying to reverse pickpocket a stack of items that can't be reverse pickpocketed, followed by an item that can.
Another could be found by having one of a large number of specific items on hotkey, then using that hotkey after giving the item to an NPC.
Another could be found by repairing certain items that should not be possible to repair, but does actually make sense to try.
Another could be found by pickpocketing a certain NPC and noticing that the gold doesn't go away.
Not that weird if you ask me...