I think (hope) that you will find the TES/ESO community accommodating and accepting by and large. Considering that homosixuality and trans-gender issues have never been thought or expressed of as "taboo" in TES games, it makes sense.
As a guild leader of The Morag Tong, I know our guild accepts all manner of life-style. I'm not sure if an LGBT-exclusive guild will be necessary, but couldn't hurt, especially considering that multi-guilding is a feature.