Every time I press play in the load screen my computer gets super laggy and I get a bunch of error messages one of which is "A required .DLL file, EKC3220.DLL was not found". Anyone know what this is or how I can fix it?

Need way more info, please. Screenies would be very helpful here.

Also, make sure you're not using a script extender such as SKSE or SD and also make sure you're not using any sort of injectors.

I fixed it I ended up needing to reinstall the 3D drivers for my video card (Radeon HD 7850) ... the drivers were from Lucidlogix for the Virtu MVP ... thanks for your help anyways