I'm running about 50+ mods at the moment and everytime I quicksave the game crashes to desktop, and sometimes when autosaving. Am I the only one who this is happening to? And are there any solutions to fixing this?

It's not so much a matter of quantity as content and how it's implemented. Some mods will conflict unless a compatibility patch is made. Hopefully TES5Edit will come soon'ish after the CK which will be priceless for detecting and resolving mod conflicts (diagnosing why plugin X does Y when plugin Z is thrown into the mix).

I haven't really tried many Skyrim mods yet, but back in the early Morrowind days there a lot of "dirty" mods, which made the game unstable. There was especially a "calm cliff racer" mod that would cause a lot of troubles if I remember correctly.

So yes, mods can certainly cause the game to crash more often. And seeing you have 50+ of them, it might be rather hard for you to figure out which one, or ones together, that are the cause for it.

I'm using over 100 mods and I don't experience crashes. If I were you I would use Wrye Bash so you know what's happening. The only time I crashed was when I was using the BBB physics mod.

EDIT: Trust me if all you use is NMM you're not gonna be able to get very far without crippling your game.

My game never crashes. I haven't had a ctd once while playing Skyrim, with or without mods.

Yes, some mods can make the game less stabile. It's up to you to either avoid those mods or to svck it up. And also, when playing with mods it's essential you check compatibility issues.

This is much like asking, can I screw all these metal parts together to make an engine?

Well, yes with the right parts in the right places you can. Just like certain mods installed incorrectly or with incompatabilities can make the game crash a lot. You should always install mods one at a time (Or at least only a few at a time) and never in large bunches. That way if issues arise, you can easily narrow it down and figure out what the problem is.

I dont trust mods released before the editor for that very reason.

I'm using a lot of mods and semi-overhauls, but I'm not geting any crashes.

But I see some oddities, like the guards patrolling around whiterun fighting only with bare hands, and the like.

This kind of problem are the result of mods created before CK, but I will stick with them, as their benefits are greater than their problems.

Or how the mods are designed , most mods do not care for performances and optimizations at all .... there is a reason why Bethesda textures are not at 4096 , there is a reason why their polycount of the models is under 5 k and not like 10000 , there is a reason why the vanilla runs smooth and the mods make lag ....

Most all of the "Better" mods out there are just overdone , unoptimized issue maker versions , not really suited to run smooth ....

so if you epereience problems look for Optimized and vanilla friendly mods...

I use around 50 or so mods using NMM with Boss and have no crashes at all. Kinda surprised really, with Oblivion I had a ton

Nope my game never crashes, as I only use mods I made lol.

I used only 13 mods in my last game and my experience was similar to the others in this thread. I have gotten maybe three or four CTDs in 200 hours of play. One of the CTDs happened before I used any mods at all. So my gut feeling is that the few CTDs I've experienced were not mod-related.

However, I notice you say it happens when you quick save. In Morrowind and Oblivion quick saving caused problems for some players in some circumstances. Years ago I got into the habit of making full saves only. I turned off quick saves in both games. It's possible that this is the cause of your problem, not mods.

As others said, pre CK mods are more prone to cause throubles. Untill we can work with the CK, each litle detail in an esp should be carefully tested and only if using an esp is your only choice. But quicksaves and autosaves are something you shouldn't use at all. They cause save corruption and at this point your save may be so screwed that simply didn't stand more corruption without crashing.

Autosaves on cell change are the worse case here, as the weakest part of 1.4 seem to be cell transitions and asking the engine to do an additional task when he is 'fighting to just continue breathing' is askig for throubles.

Ninjaed

I use Wrye Bash and Bain (and NMM configured to download to Wrye Bash installers to keep on top of updates) I have 26 mods at present doing various things that I frequently swap and change and add to and remove... and quite a few texture mods too.

I'm getting no crashes at present, I have in the past from my over clocking but nothing mod related.

I think if you use Wrye Bash (and BOSS) and BAIN to repackage non Wrye Bash friendly mods and keep on top of updates, sort out conflicting mods you will be less prone to issues.

As a note... My 9 year old son plays Skyrim on his PC and I've installed NMM and shown him the way to the nexus website where he downloads various mods and textures, he gets crashes, quite regularly.

I didn't us a lot of mods and most of the time I'd be OK in game, but I almost always crashed upon exiting the game.

I'm very hesitant to use .esp based mods before the actual editor comes out, I only use 2 right now.

be sure your drivers are update. its my opinion that games crash just as much from outdated drivers as conflicting mods. if your running a nivida card there is even drivers specifically geared to skyrim for example.

I have dozens of mods, using both SD and SKSE and no stability issues... compared to Oblivion where my game kept dying on me once even lightly modded.

Ditto on the "be careful" advice. Until the CK (or CS or GECK, depending) is released, I don't trust .esp-based mods. Some of the pre-CK modding tools out there are awesome efforts and can be very useful, but some parts are best guesses (at best), so problems and conflicts can and do happen. You pays your money, you takes your chances.

As a general rule of thumb for pre-CK mods, I've found that retextures are generally safe (provided you have the horsepower to handle them). Environmental tweaks (lighting, color and such) are typically harmless; not always, but typically. Scripting, interfaces, outside utilities and such can cause issues, so you really have to trust the authors. Playing mods for previous Beth games will give you a good feel for whose work is really solid. Beyond those, you need to know what the mod(s) do and what they do it to. And, of course, if any of your mods are dependent upon other mods, load order is massively important.

I've only used about 8 mods with.esps/script extenders and 30 or so mesh/texture replacers for Skyrim. Most of the esps I did myself and only change little game settings or fix a texture path. Since I figured out how to get more than +2gb on a 32 bit system I have had 1 crash. That was after a 2 hour straight playthrough.

It all depends if the mods are installed correctly and if they are bug free whether they crash. Even then sometimes the engine likes to throw fits. I would say hold off on the .esp mods until a week after the CK comes out unless you know what you are doing.

Edit: Turn off Autosaves right now! They only cause bad things to happen from my experience. It's better to make hard saves and keep only a few of them around at a time.

I've been running just 3 mods(one of which was made by me) and I've only crashed 1 time and that was before I installed any mod. I can play Skyrim all day(10hrs+) and not crash at all.

Yes, but only because I always insist on running into the Riverwood Trader Door without saving first

The only cause for my crashes so far is an old SKSE version (version was meant for last beta version of 1.4). So far since then, it's been smooth sailing for me. I've gotten fairly used to figuring out proper load orders since Morrowind, and how to determine conflicts, albeit a time-consuming and horrendously boring and irritating process.