Plenty do. I have bottles of Alto wine, .5lb each, like 9 Giants Toes, 1lb each, and several of the Claws for those dungeons, again .5lb each. I would like a mod that makes all quest items weightless too... I'm guessing alot of these are quest items on accident? I have built up like 15-25 pounds (AT LEAST) of quest items as well.
The items have weight set in their base forms so it shows up in the menu, but it doesn't count against your carrying capacity.
Not sure why they didn't just set the weights to zero to make it obvious.
Edit: oh right, there are quest items that are unflagged after the quest is completed that remain in your inventory.