Assassin Suit
All-American
Holorifle
Like others said, I'd get bored with only two weapons. The variety is what keeps me coming back to play.
Even though I didn't choose it, the Ratslayer proved to be a darn good and effective sneak and snipe weapon. I got it as early as I could in the game. Even if it meant running away with it before all those Giant Rats in the cave could surround my weak, early level character (a stealth boy that came in very handy). I also found the 9mm SMG (particularly Vance's) to be great in close combat.