This will result in being able to one shot anything in the game provided you can sneak up on it. It will require the completion of the dark brotherhood questline, and a handful of perks. After the dark brotherhood sanctuary in dawnstar is yours, speak to delvin in riften to purchase the bedroom upgrades. In the sanctuary, to the right of the bed on the bookcase is a set of the dark brotherhood gloves that carry the 2x backstab enchantment. The thing is, these are enchantable. With the proper perks, it is possible to stack 5 effects on these gloves, though most are magical fortify and regen possibilities. However, with a fortify one handed, and a few other gear enchantments that also carry the fortify one handed, sneak attack damage can be boosted off the charts. With the five one handed perks that increase damage, (100%), several fortifies, (100-112%, more with proper potions and smith enchanted gear), these raise base damage to over double the listed value on the dagger. Now, the assassins blade perk raises dagger sneak attack damage by x15. Wearing the aforementioned gloves will increase that to x30, resulting in a massive one shot and a kill animation practically every time. Also to note for the assassin players, the blade of woe requires no materials to upgrade. It scales with player level. Simply return to a grindstone after leveling a bit, and resmith it for more damage. Any enchantments can be stacked on this for even more damage and destruction.