I got hit with an Ice Spell at some point I can't remember, but even after it stopped the visual effect kept going, and I was covered with a blue frosty aura and an occasional ice spike would come jutting out of me. So I saved and reloaded that, and ended up with a giant ice spike permanently stuck in my armpit. I ended up having to reload a couple of saves back to get rid of it. Just thought you should know Bethesda.