I'm incredibly pissed at the super DNA ending. Seriously. Banana flies have DNA just as we do. We have DNA just as ebolaviruses do. DNA itself is nothing. DNA is a chemical amalgam that directs the construction of proteins and in the long shot they direct your bodily functions. There is no super DNA. There are only DNA functions that end up directing superior life forms, but it does not do such magic as magically giving people... whatever powers they give in the ending. What the hell is the purpose of the ending anyway????
If you go modifying human DNA it will die because the human body will lose its ability to maintain itself. Simple as that. Even a small modification to DNA can be fatal, just one aminoacid jumping from one place to another among billions of its comrades may define the line between healthy life and brain tumor.
I agree that it svcks to have Shepard die, but given the way things played out, what are the chances Shep would live without being rushed to an intensive care unit? Shep got directly hit by one of Harbinger's anti-ship weapons, and depending on what you think of the ending, is either in one of the deep parts of the Citadel or in the heart of Reaper controlled london. He/she's unlikely to get the medical attention needed to save his/her life.
Shepard survived having Normandy shot up, Shepard running out of oxygen in middle of space, surviving the intense flames of entering a planet's orbit, survived on the ground for Newton knows how long, survived being passed from one owner to another.... The list goes on. My Shep took a good breath, that means she survived. There is no reason for BW to have her take a breath unless they mean something.
I don't understand why the need to drive Shep for these unnecessary sacrifices. The "kill the Synthetics" ending would be very adequate IMO if it didn't blow up the Mass Relays in the most idiotic manner. So EDI dies, so Geth die, not a big loss Synthetics can be rebuilt if we want to. But the damn Relays? What's the point? It could have been a very happy ending without that stupid plot device Can't-Give-You-A-Good-Ending crap.
EDIT: A good theory suggests Shepard never even left Earth. She was knocked out by Harbinger and that's her taking breath.
So, this is all just a facade to make us buying the DLC to correct ending they knew would piss off people.
You've never watched the West Wing?
http://www.youtube.com/watch?v=JR09Gt9DTKY Or his voice actor, anyway?
It ran in Finnish television for a few years but I never watched it for whatever reason.