Vampire: The Masqerade - Bloodlines. It's not entirely an FPS, as it can be played with melee weapons in third-person, but then again, ME isn't a FPS at all either.
Yep, another vote for Bloodlines. Brilliant game.
Star Wars: Knights of the Old Republic. Not very shooter oriented game, but it has laser guns in it...
Not first person though...
how is Metro 2033 an RPG?
It isn't.
Both those Deus Ex's mentioned, Vampire of course, and might I suggest the STALKER series?
Yeah, S.T.A.L.K.E.R. games are very light on the RPG aspect, but they're fine games.
You could try http://en.wikipedia.org/wiki/Alpha_Protocol, gameplay is like a mix of Mass Effect and Deus Ex: Human Revolution, set in the modern day.
Too bad it was awful
