What's a shame for me is the inability to 'Stake' vampires that you happen to come upon sleeping. That would've been nice. I mean, I open a casket and see a vamp laying there, and I get all excited thinking I'm going to do a Van Helsing slaying, and all I do is slash them. I tried to pickpocket, hoping there'd be a 'Stake' thing, but nope. How about it Bethesda? They can bite people while they're sleeping, how about taking out a sleeping target? Staking for vamps, and something similar for 'mortals'.
Get out your shiney silver sword, and lop their head off. Also van helsing style, albeit slightly more retro then what most are thinking.
1 handed, archery, sneak, restoration, light armor. ( ironicaly i preffer to wear the black vamp armor with nightingale boots and gloves)