Umm... none will impact performance? Are you kidding?
The HD texture pack will be about double the memory usage, and the FXAA would add more strain to the GPU.
OP, if your computer can only run mid/high range, then don't bother. The game looks good as is. It can use some improvements, but, but if your computer isnt up to par, you will only be hurting yourself.
I suggested the Lite and lo-res versions of those BECAUSE they don't have the effect you stated. Skyrim HD lite is only 1024X1024 textures, and the other low res/med res files are smaller. Lush grass/trees didn't drop my performance at ALL (And are advertised as such on their download pages). So, NO, those WON'T have a huge negative impact on the performance.
Edit to add: I am only running the game at Medium to high settings (granted I've tweaked the hell out of those settings because I'm pretty good at it) and Running every mod I listed I still get 45-60 FPS in most places and no lower than 20-25 in bottleneck zones.
My system:
Windows 7 Ultimate SP1 x86
Intel Pentium Core 2 Duo 2.8GHz
4GB DDR2 1024 MHz RAM
nVidia GeForce 9800GTX (BFG Factory OC to 833 MHZ) with 768MB GDDR3 VRAM