Apparently I'm not the only one experiencing this.
Playing on a self built rig, Win 7 64-bit, NVidia GeForce GTX 465, 8gb DDR3, Core i5-2500K @ 4.0ghz.
The game installed fine, plays and looks great (aside from the wobbly shadow edges).
But the problem is that I'm playing the game. Everything seems fine. And the *BOOM* I'm staring at my desktop. No error messages, no warnings. It just happens instantly, and I lose everything up until my last save point.
I've been playing 4 hours, and it's happened twice, at completely random times in the game.=schleima
This is been happening to me also, after playing for 3 hours on the 11th and the morning of the 12th. I get up boot up pc make coffee etc... play 10 min and BOOM CTD! .. thx bethes thx a lot! Gret game but this is not what i was looking for : random coffee breaks ??
Anyway they better get a patch out ! SOON!
Just to give a brief explanation of what if tried so far:
First :: What does not work?
-It does not work to edit/change any setting of the sound etc to 24bit, 16bit..none, none, none... this is for those who gets the crash upon launch ..not random CTD's
-It does not work to change the shadow detail. to what ever setting...
-It does not work to lower any graphic setting... (this is b*llsh*t are Bethesda now launching games that we must play graphics on the lowest, with high end hardware that cost us a arm and a leg??)
-It does not work to play with a controller (one guy posted this on a forum lol) -- what the hell - if we want to play with a controller we would have bought the console version.....
-It does not work to play without steam client running. - this time its not steam! ---low textures on ultra settings ??? wth?
*PS-its does not work to verify steam file integrity.. its bull sh*t .. been there tried that.
- not a steam issue - this is a developer thing - they have to fix it...can't let such a great game be negative discussion on forums all over.. for peet sake .. we should be busy playing the game .. and discussing what game tips etc we can do, character builds and quests!!
Second :: What does work ?
- This is my research of 3 days thus far...
- Well Nothing that has been mentioned so far...NOTHING!!!! - this is at there problem .. Im no pro at dev, programming - but it seams this game is underdeveloped or not complete,,, that the crashes..un-rendered textures, some claim to see purple/pink textures. -maybe a cache error who KNOWS??

It may be the above mentioned , it may be something simple ,, al I know is that its not WORKING,, and all we who PAID for it , want to do is : PLAY.. PLAY.. Im not interested in becoming a programmer or developer ....
So what do we do wait... wait ..wait...

LAST:
This is my conclusion .. I dont want to sound negative,...,,,., so lets keep are hopes up and keep trying new things ,, so that this thing can be FIXED FOR REAL..
GOOD DAY TO ALL ! ENJOY LIFE! -- even when Bethesda disappoints us...LOL

..Good Luck to you Bethes,,,,
Cheers
Wolf xD
**PS o yeah -- here is my system specs: Intel i5 760, Gigabyte Geforce GTX 460 1GB, Trancend axeram 4GB DDR3 2000Mhz, 1TB Seagate Hardrive. Coolermaster 750W PSU.