Nop, it's like that. The 'replay mission" feature actually load up the equivalent "mission : XXX" save. With the progress you did last time you played the campaign.
So if your latest playthrough was, say, a full low chaos - no powers run, every mission available to replay will feature a low chaos setting with no runes spent on powers. You will also retain the charms you found so far. If you start a new game and go on a killing spree with High Chaos setting, though, you will find out that your low-chaos/no power replays are getting replaced.
it's kind of lame, in a way, yeah. There should be a mission parameters customization or something. Like choosing between low and high chaos, which upgrades you have, what powers, etc.