This seems to be the most popular option:
http://www.reddit.com/r/skyrim/comments/mto5b/my_experience_playing_unarmedno_offensive_magic/
It involves a Khajiit, heavy armor gauntlets, Fist of Steel perk and the Pugilist Gloves.
Just come to think it.
I love creating new characters and this time i'm trying to build a shaolin monk.
He would fight only with his fists.
There's no 'unarmed' but i guess one handed skill works.
Someone can confirm?
And ideas, any suggestions?