I don't think it does. SkyRe used to have a vampire perk tree but in a new update they said they removed it for dawnguard so as far as i know it doesn't. Not completely sure as i have just gotten all my mods put together and ready to play.
I'm in the process of reinstalling Skyrim right now, so please say if something goes horrenduously wrong while playing with SkyRe+Dawnguard, so I know whether to get it or not.
Crashes on startup. I saw the Bethesda start up screen and heard the very initial music and it crashed.
I removed mods like Deadly Combat that probably would have been... redundant..with SkyRe and it still crashes.
Anyone else care to try?
Deactivated SkyRe and game runs fine.
SkyRe looks like a great mod but I don't think its compatible yet.
EDIT: Okay I'm dumb. Don't install the compatibility patches for jaysus swords and such if you don't use that particular mod. Appears to be working now, although I don't have a vampire tree...
SkyRe runs with dawnguard. I've been using it since I reinstalled everything and its fine. Just make sure you have the right compability patches. No vampire/lycan perk tree probably till the update, but everything else runs fine.