On Ultra, you'd need something that would be pretty costly (600 gen NVidia). But, the 500-series (even low range) can run on high with problems (as long as you're not running it in 3D Vision with the glasses). Is it worth it? For me it was worth every penny to get my new Alienware laptop to run on Ultra AND to be able to run any new game at laughably quick FPS (Skyrim runs over 60fps on Ultra). The biggest difference you'll see is the high-res WITHOUT FXAA. "Smoothing" is both more intensive and kills the "pop" of the models. With higher res, you don't need it, and SKyrim then really comes to life (plus the extended draw distance, which is also killer on Ultra). For a Skyrim-only machine, though? No, probably not worth it unless you can pick up a used system for a few hundred bucks. Even still, you're not likely to get anything really GOOD. Yes, you can play with whatever UI you want, you just have to buy the controller. IMO, PC keyboard/mouse is far superior to any "controller". Give yourself a chance to grow accustomed to it and you'll probably, as most do, agree. Mods, I can't answer, I don't use them. Too often it's too easy to break your game (completely) when using mods. Highest settings being Ultra, you'd need something along the lines of 8MB, mid/low-end current generation vid card to be minimally playable (solid 20some fps). For a laptop, you're probably looking at $2-3k. For a desktop, $1-2k. Or, if you're so inclined, you can pick up something low-end, or high end last gen and run Skyrim on High instead of Ultra and get MOST of the eye-candy.