First and foremost... in the menu, you have to click on the end of the word in the middle of the last letter or you will keep going out of the menu options.

On to the stuff of interest...

Google a program called GlovePIE. I had to use it for Deadspace, which also had a bad interface.

With this program you can customize your interface and save the settings you created. All you have to do then is just load them up and play skyrim.