Does this game utilize SLI or Crossfire setups?????

Now a days it's not a matter of the devs supporting SLI/Xfire, it's a matter of the drivers being there to play nice with the engine.

There's an SLi profile for Skyrim availabel now. Just go to your Nvidia control panel and hit update.

Don't know about AMD, but I'm sure they'll have a xfire profile ready soon, if not already.

I have not seen much word about it, but I would think so. Since the recommended requirements were just for high settings, not ultra, I would think it would utilize it. That is my best guess though...

Like Kinthalis said, a Crossfire profile may be ready soon. Who knows?