I'm wearing the muffle enchanted dark brotherhood boots and using the invisibility spell and yet draugr and npcs etc. Still always discover me if i get too close to them. I would have thought that muffle together with invisibility would make me completely undetectable until I attack or activate something.
Dunno if it's the same, but...I have to un-equip and re-equip the backstab gloves to get them working properly. Maybe the same issue plagues the boots.