Tweakguides is a superb repository of game tweaks and settings
he is working on a tweakguide for Skyrim which will have all the goodness in it but for now he has suggested a vsync tweak to help with FPS and also mouse lag
"To disable VSync in Skyrim, add iPresentInterval=0 to the bottom of the [Display] section of the Skyrim.ini file in the \Users\[Username]\My Documents\My Games\Skyrim directory."

this is the main website: http://www.tweakguides.com/

might help some people