Do I need to have some kind of merg or wyre batch if I am playing with Asis, Deadly Dragons and the Skyrim Monster mod?

I did use BOSS after installing these mods, though I notice some enemies acting strange... I ran into a sea dragon on the road and it wasn't hostile to me even after I attacked all it did was kind of waddle around on the road.

This issue sounds familiar, although, I cannot rememer the exact cause. Either there is something wrong with the way AI is scripted in the mod in question or this issue happens when there is an "AI overload" (Probably can be both).

ASIS modifies no individual AI's, so if other AI's work properly, that wouldn't be the culprit. It does increase the number of AI's processed via increased spawns, so you can hit the max limit. I always forget what the GMST is for it, though.