my problem with the guns is sometimes when equipping a weapon on my back or readying a holstered weapon it will actually shoot with a spread of a shotgun or even worse, ive seen my bullets land right at my feet when ive aimed down range with a sniper rifle. a perfectly accurate perfectly undamaged rifle at that. but it would resolve itself after switching to another weapon and switching back. Ive had the same issue in FO3 and it baffle me why they havent fixed this.
But this can definitely be a problem with your sneaking and your bullet decides to everywhere but where your pointing, leading into a [censored] up situation.
also your best bet it to not use true iron sights moed, the iron sights sway and is not representing where the bullets flight path is.
If you want to check how far the sights of your weapons are unaligned. switch to 3rd person, aim down your sight while still in 3rd person, and while holding up your sights switch back to 1st never letting go of your sights button and you will see the crosshairs where it lines upw ith the sights. The bullets always try to move along the sights path in 1st person, and almost all weapons are off by a huge margin. in particular teh hunting rifle is one of the worst.http://img841.imageshack.us/f/falloutnv20101028073543.jpg/