From the sound of things with the patch, new Form and Ref Objects are being added to the ESM. Last time this happened, there were more than a few FormID Mixups.

Those who know what they're doing with FNVEdit can use that app to find any errors with improper FormIDs.

Yeah I am really not looking forward to seeing how much this next patch will break.

Man, did Fallout 3 have this many issues with each patch? I joined the community, like, AS the last patch came out, so I didn't see any of this.

I don't believe so. That being said, fo3 had other serious problems with patches. The whole converting all esps to esms using master-override was spawned from a lousy fo3 patch.