Other than a couple of relatively brief, trial-run characters, I'm still on my first playthru. But, as with Oblivion, I've just assumed that one of the goals with my first playthru (and this forum helps too) is to learn what leads to becoming OP. In turn, subsequent playthrus will likely turn out to be even more fun and rewarding for me because of this knowledge.
I *much* prefer that the options remain, even if I choose not to use them (or not use them to their fullest possibility), than they disappear altogether.
Exactly, the options are there to make you 'Overpowered' or to make your character slightly less God-like.
The quickest ways to deity for me are stated above but I'll list them again :
Enchanting + Smithing
Archery + Sneak
Destruction + Conjuration
Notice that all of those are decent stand alone, but in tandem with their counterparts... they become quite OP'd in my opinion.