No, I can kill it. I just can't do anything else with it. It doesn't even say "wolf" when I point my crosshairs at him. It's not like it really bothers me. I'm just paranoid and waiting for the other shoe to drop. My luck it'll be every hostile within ten miles, all spawning in while I'm sleeping.

Thanks for the mod link; I was using that for a while, then switched over to Martigan's de-bloatifier. Corpses will still turn into ashpiles as intended with it, and it handles nirnroot glows a bit better IMO. Made my own mod for handling dropped weapons, so that's all good.
Edit: Looks like I could be a lot worse off. Thank the Nine I'm not getting this: http://www.gamesas.com/topic/1354617-massive-spawn-inside-whiterun/