I dont know why but beta 1.5 crashes my system at random. Before 1.5 the game ran perfect so I have reverted to 1.4 and I have not crashed sense.

I am running 43 mods and the high rez texture pack and here are my system specs.

FX 8120 3.1GHZ x8
8gb of PC1600
560TI 1GB
onboard sound
500gb Sata 3.0 Hard drive for the OS and a 750GB Sata Hard drive for the games
XFX 550 true watt power supply

Try posting in the beta forum, since 1.5.24 is currently only available as a beta release.