Hello,
Recently my mouse and keyboard stop working in Vegas. I don't know if anyone has run into this problem or not. help would be appreciated.

Do you use a controller at all with your PC? Having an xbox360 controller plugged in will make the game default to using that, and disable the mouse and keyboard. booting the game without the controller plugged in should set it back to use the mouse/keyboard. That's the only 'in-game' factor that I know of that disables m/kb control.

If it's not that, then I don't know... system issue?