Same here... happened only once out of 2 fast travel. Been scared to FT from that point on.
So far, I've been plagued with the following issues:
- Fast-travel crash (50% so far, not using it anymore)
- Hyper-speed mouse in menus/vats (fixed using .ini hack)
- Slowdown bug around NPCs and when looking at specific areas.
- The reverted savegame. Lost about 30min of gameplay. Got frustrated so went on a rampage and killed all the escaped prisonners in the prison.

lot's of XP!
- Minor glitches here and there. Mostly with my Steam Caravan pack shotgun anim glitching, character anims not really fluid... the usual FO3 stuff I guess.
I'm usually not one to complain, but this game is really buggy. I hope they support the game and release regular/quick patches to fix most annoyances that prevents us from enjoying the game to its fullest.
-Flat