I'm thinking of situations where one might, say, plug in the wrong drive and not realise until its too late. Because, y'know, sometimes we do things that are completely, utterly stupid

. Having two backups means that if you manage to FUBAR one, you can just fall back on the other instead of beating yourself to death with your palm.
Of course right after telling you that shouldn't happen with a proper backup, I just formatted the wrong hard drive setting up my new computer wiping out the data :facepalm: Currently restoring 550 gb. Only lost my linux ISOs (which I didn't bother backing up since they go out of date so fast it usually isn't worth it)
Something that doesn't seem to have been mentioned yet but that's quite important is that before you settle into a backup routine too much you should actually try to restore from one of your backups (on a system other than your primary one, just in case something doesn't work right). The basic rule is that backups are easy, but restores are hard- the last thing you want to find out after your hard drive starts giving you the click of death is that those backups you made had some problem that prevents you from restoring from them.
Indeed. A backup untested is nothing more than hope. Of course if you don't have a spare machine to test the restoration on, just use a virtual machine.