The easiest way to deal with a single DeathClaw is to equipped a decent Shotgun of sort , my personal favourite is the Riot Shotgun , somewhat get the Deathclaws attention and wait for him/her to charge , havn't a clue how you tell the difference in gender LOL. Anyway , once they are in a close range , [HINT] : Not close enough for it to hit you , go into V.A.T.S mode and aim for either it's head or legs. With luck on your side it should go down within the first three shots of the V.A.T.S mode , otherwise you'll have to give it a good old shot out of V.A.T.S mode. It's relatively simple and helps if you have 10 Perception on your S.P.E.C.I.A.L abilities. This helping you locate it on the map easily. Thanks for reading and I hope this helps.
P.S if it's a group just walk away , repeat just walk away , unless your man enough to take them all on.
