If you are a Mage with Destro, Illusio, Conjuration focus.
Would you pick Enchanting or Alchemy? Can't have both, perks that is. Or none? And why..
this completely depends on how you're going to be using the pc: strict rping or just going for power.
my hybrid power build has both, but, only the perks that truly lend towards being godlike.
for me, a more magic-centered character would stick with enchanting. but, again, it depends on your rp and gameplay decisions. both are powerful.