So we know that two of the playable races are Humans and Ghouls so far. Why not do something somewhat like DragonAge (it's the first game that comes to mind that does this) did but expand it a bit more. When choosing your race you pick a "starting place" and this dictates your starting skills.
Example would be say I were to pick a human. After choosing such you could pick whether your origin is from a Vault or born in the wastes. Being born and raised in the wastes would maybe give a bonus to Survival skill and a few other things that would be in a "wastelander" origin starter pack versus someone born in a Vault who would have a bonus to say maybe Science skill and other things of that sort.
This would bring up different starting areas and possibly different starting "kits" for characters given their origin during character creation. I personally think it would add a layer of "realism" to an extent to character creation since Vault Dwellers wouldn't know initially how to survive out in the wastes as well as a wastelander


