Having trouble with this, I've got around 80 melee weapons, level 13 right now, I use psycho and med-X vs. them, but unlike with my sniper character I can't really pick them off 1 by 1 from long distance. When more than one gets on me I'm toast, and even vs. just 1 I can die sometimes depending on my luck.

Any suggestions? Maybe I should use a gun/energy weapon to attempt to draw them away from the pack 1 by 1? Blocking doesn't seem to reduce much of their damage.

just want to say that your a very brave soul...

am trying to fight a 4 meter tall fang monster that can rip steel with its 20cm fangs, with my fists.

why is this not working.

well good question

Pull them one at a time with silenced weapons. Use knockdown(slam, paalm, or the special move knockdowns) abilities to keep them from [censored] your face off. Maybe get palm at level 14 and come back.

You never know, they may be so supprised that your trying to take them on with a stick that they simply run away. Or not . . .

Seriously though at least in FO3 you had the dart gun to stop them doing their lunge attack, your gunna struggle without it.

You are better off using Unarmed than Melee.

Paralyzing Palm is absolute win against 1 Death Claw. If you get surrounded ... well then you are a gonner.

This is on Very Hard, might be different in lower difficulty. On VH you simply cannot kill them fast enough with melee weapon before they eat you alive. The knock down perk help a lot though. I managed to take a few out with knock knock (1 at a time however).

you need power armor and an advanced fist weapon like displacer or pushy. unless you have a super sledge/rebar hammer with 10 strength, melee wont help you until you are at super high levels.

at level 30 my guns character has trouble against a DC with the fire axe

[Eh, I just looked. You can't get palm until level 18. Also noticed you said melee. Which basically, like I said, use knockdowns(super sledges, knock knock, who baby et.) or super slam while getting them one at a time.