I was thinking it would be fun to go exploring on hardcoe trying to make it from one point to another that is fairly far away while only carrying the very few essentials I was thinking: (all fully conditioned)

Combat Knife
Assault Marksman- 200 ammo
2 Grenades
5 Stimpacks
2 Lots of high powered food (gecko steak or bighorn meat)
4 Bottles of purified water
Merc Grunt outfit

Rules are I can pick up more of any of these things but only to fill the slots of things used, so If I drink 1 water and use 55 bullets, I can only pick up 1 water and 55 Bullets. I can repair any of these things if I find copies but I cant carry the copies with me I have to repair then and there. If I find more food or water I'm allowed to eat and drink it as long as I'm not carrying more that I've allowed for each item. I have no money to buy any more supplies with.
Now I just need to choose a starting point and an end point

Nipton to nelsions air force base

Sounds good. Go the Primm/Goodsprings route.

Would be impossible unless he's already been up there

I'm not going to fast travel Im doing it manually the whole way, so start at nipton, head to primm then good springs then to boomers base.

Impossible? I disagree. Sounds like a challenge then!

I try to go without manually saving... only letting it save if I reach a transition or sleep. But sometimes it's difficult with the occasional CTDs.

There is a damn good idea, Im going to take it on board and definatley do it.

No, I get my ass handed to me just fine without making it easier for them... but I'm on Hard and using hardcoe Mode. There are probably mods out there that will affect only the thing you want to affect, like the damage taken by your character.

lol I know i often get destroyed but I put up a good fight, I just think this will make me appreciate all the other things i can carry, help me pick my fights and just be funny.

hardcoe mode doesn't matter much, combat difficulty does. So what's your guns skill and what diffilculty you have in mind ?

I sort of do what you do, but I try to carry only 2 bottles of Nuka Cola and 2 bottles of Purified Water. If I eat, I need to take a drink as well, since in real life I would never eat without having a drink or two or three. But of course I watch my weight and only have one bottle in New Vegas. LOL. :foodndrink:

*edit* I don't use Stim Packs unless I absolutely have to. So if I am in combat, I use a Stim Pack, then wait about a minute before I use it again. I drink from a water source to heal myself, since we can't bandage ourseleves without Stim Packs, I just pretend I am bandaging and taking washing up when drinking from a water source. It takes about 2-4 minutes to replentish my health this way, but then again, it would take a long time to do so anyways.

If no water source near by, then I find a doctor to heal me.

Difficulty would be on medium, my guns for current character is about 40 give or take a few.

I used to do something similar in FO3 - strip myself completely naked - nothing with me, no weapons, caps, armour. Nada.
Then fast travel to someplace far from home and just try and make it home alive, no fast travel allowed. There wasn't a hardcoe mode, so you didn't have those problems, but it was still huge fun.
I used to pretend I'd been abducted by aliens in my sleep, probed (ahem!), and then dumped somewhere like a discarded lab rat, crying and unable to sit down...

I remember one great night's play, when I realised I'd previously stripped the area I was in of everything useful, so there wasn't even a lowly lead pipe available... I hid on a hill for 20 minutes watching some raiders do their patrol near some yao guai, hoping to loot a corpse after they met up.
Then all hell broke loose when some renegade BOS wandered by and did the job for me. I got a few raider corpses to loot and I was sorted.
Very little ammo, though, so the journey home consisted mostly of avoiding radscorpions!

I'm gonna try it in FONV when I get further into the game, I'm not at the stage of having to invent my own entertainment in it yet.
Should be interesting with hardcoe mode enabled, trying to scavenge for water and food... All those barrel cactii and buffalo gourd plants suddenly become very useful.

xD lol watching your weight and how you need to drink after a meal lol, Ill only use the stimpacks when its crucial to.

My rules for ammo are different. I take into consideration that I can only have so many magazines for my weapons so when I go to my place in Novac to stock up, I only carry 6 magazines' worth of ammo. I've reloaded magazines before in real life and one thing's for sure... putting bullets into a clip is hard enough as is without trying to do it while you're getting shot at or running from something. I can restock at a merchant, but I can only restock if I'm carrying the weapon the ammo goes in.

Now when it comes to weapons, I only carry a primary weapon, a secondary weapon, and a sidearm.

Those are my general play rules though. I'm thinking about trying something like what you're describing though. It sounds like a fun challenge. Perhaps I could try to make it from the North Passage to my motel room in Novac.

Quarry Junction to Nellis AFB via the summit of Black Mountain. Weapons: shaving razor and BB gun.
No ammo or clothes.