...I pause to reflect on hardcoe eating, and I envision Jason Statham, eyeing up a tasty chicken sandwhich like it's a bomb, or it just shot his best friend before angrily and furiously eating it.
On topic, once or twice a day wouldn't bug me. In the Chris Avellone interview that just hit the forum, he mentions how one dev died in 60 seconds in Hardcire Mode, but that may have been sped up. I'm really hoping it isn't like the original The Sims game where you had to pee or eat or sleep every three minutes.
J.E. Sawyer said on some other thread that they were testing it out, so it was an accelerated dehydration rate.
And I agree, twice in an in-game day is more than reasonable. I usually set the in-game time so the days don't go by so quickly, so it may be easier for me, but what the hell.