On Master Mode. It's useless. I've tried it. The only way to beat the game on that mode is by exploiting.
I can't tell if this is serious or a bad joke. . .
Many people, myself included, have dead is dead Master playthroughs that have finished all major story arcs without using stealth, enchanting, smithing, or alchemy. I went a little further with mine and didn't purchase any items from vendors.