Personally, with a character who I decided would fly into psychotic rages upon consumption of Nuka-Cola, I let him get captured by Caesar's Legion. I then stormed the camp, fueled by the murder-inducing Nuka-Cola, and killed Caesar and all of his soldiers. After that, I walked casually into Caesar's tent up to Benny, who was bound and on his knees before me. I (mentally) told him, "From down there it must look like you've had a 14 carat run of bad luck. Truth is... Game was rigged from the start."
I then ran at him, and hit him directly in the face with a power attack from the super sledge. My Bloody Mess perk kicked in at exactly the right time, sending his various bits all over the tent from the blow as if it came not from me, but from Thor himself, swinging his mighty hammer.
So does anybody else have a fun story about the checker-coated rat's death?
